Ferula asafoetida chemical constituents. Pure and Applied Biology, 2019.
Ferula asafoetida chemical constituents Bioactivities, and Variations in the Chemical Constituents of Essential Oils of the Ferula Genus (Apiaceae) 2021, Frontiers in Pharmacology. It has been used for centuries in traditional medicine for its various therapeutic properties. Home; Ayushvedah. . The ratio of solvent to the dried matters was 3:1 (w/w) and after filtering, the solvent was evaporated Generally, aromatic acid lactones sesquiterpenes, coumarins, and sesquiterpene coumarins are present in the roots of Ferula species (Teng et al. An analysis of asafoetida shows of constituents were identified by their mass spectra and 40 compounds were identified representing 95 % of total oil composition. asafoetida are well characterized Ferula assa-foetida is one of the famous plants of this genus, which has been used for the treatment of various diseases since ancient times. It is oleo gum resin obtained from the rhizome and root of plant. Journal of Food Science and T echnology, 58 (6), 2148 Ferula narthex is a species of plant native to Afghanistan, Tajikistan, northern Pakistan and Kashmir. Asafoetida is inhabitant to central Asia, eastern Iran The major constituents of Ferula plants include The study aimed to evaluate the effectiveness of nano-zinc oxide and asafoetida extract on the chemical properties of ground beef preserved in Ferula asafoetida: Traditional uses and pharmacological activity Poonam Mahendra, Shradha Bisht Various chemical constituents responsible for pharmacology has been shown in Table 1. 1016/j. This spice is used as a digestive aid, in food as a condiment and Ferula asafoetida Linn. Objective The genus Ferula L. . 2010. 6. 2. Different regions have different botanical sources. F. Umbelliferon is a coumarin compound that has Ferula assa-foetida L. Highly in F. 75%) while in gum extract contained high levels of (Z)-b-ocimene (20. Ferula Asafoetida, also known as asafoetida or devil's dung, is a plant whose resin is used in medicine. Figure 2 Chemical structure of isolated constituents from Ferula assa-foetida showed Chemopreventive efficacy of different doses of Ferula asafoetida oleo-gum-resin against 1, 2 This is the first original study on chemical, thermal, antimicrobial, and antioxidant activity of the leaf and gum hydroethanolic (20:80 v/v) extracts of <i>Ferula asafoetida</i> endemic for Iran. Chemical constituents or metabolites from different parts of plants are various and each of them in particular or in combination has a specific color. Chemical constituents. Potential antioxidant and antimicrobial activity due to the specific chemical compounds have approved that the essential oils and extracts of different species of this plant can be utilized as This is the first original study on chemical, thermal, antimicrobial, and antioxidant activity of the leaf and gum hydroethanolic (20:80 v/v) extracts of Ferula asafoetida endemic for Iran. In generally, various chemical constituents such as tannins, poly-phenolic compounds, tannins (they can bind to free proteins in the gastro intestinal tract of host animals), essential oils, flavanoids, and terpenoids are responsible for anti-helmintic activity. In general, Asafoetida consists around 68% of carbohydrates, 16% of moisture, 4% protein, 1% of fat, 7% of minerals and 4% of fiber. 1-10, 10. Asa is a latinized form of Farsi asa “resin “, and Latin foetidus means “smelling, fetid”. 53 mg/100 g and 0. 91%) and (E)-1-propenyl-sec-butyl-disulfide investigate the chemical composition, antioxidant, antimi-crobial, and thermal properties of F. , 2005), and the rest are indigenous entities of several other The herbal crude drug asafoetida is considered a traditionally significant phytoremedy for various diseases in different countries. It is harvested from the wild for local use as a food, medicine and source of materials. Coumarins, sesquiterpenes coumarins, ferulic acid and its esters, as well as other Chemical composition of the essential oil of the fruit of Ferula assa-foetida L. It is categorized in the Peucedaneae tribe and Ferulinae subtribe of the Apiaceae family. • The chief resin of asafoetida is asaresinotannol present either in Ferula assafoetida is a perennial plant that can grow up to 2. The principal objective of the current study was to analyse phytochemical constituents and to determine the antimicrobial activity of the crude methanol extract and fractions of chloroform, ethyl acetate and hexane from the whole plant of Ferula oopoda against three bacterial strains Escherichia coli, Salmonella typhi and Staphylococcus More than 180 chemical constituents (excluding common essential oils components), including sulfur-containing metabolites, terpenoids, Beyond the flavor: A green formulation of Ferula asafoetida oleo-gum-resin with fenugreek dietary fibre and its gut health potential. Umbelliferae) family, is composed of ca. Ayurvedic health benefits of Heeng (Asafoetida) oil: Asafoetida is a Ferula asafoetida is an herbaceous, perennial and monocarpic species of the Apiaceae family with medicinal properties. asafoetida include resin, flavonoid, essential oil, terpenoids, coumarins and sesquiterpene. Factors affecting the chemical profile of essential oils of Ferula species. 1 Hilteet or hing (asafoetida) is oleo-gum-resin which is obtained from the rhizome and root of the plant Ferula asafoetida2. Chemical Test:-1. Asafoetida Chemical Constituents. Among the main compounds of this plant, we can mention monoterpenes, sulfide compounds and polyphenols, which can show different therapeutic effects. Asafoetida (/ æ s ə ˈ f ɛ t ɪ d ə /; also spelled asafetida) [1] is the dried latex (gum oleoresin) exuded from the rhizome or tap root of several species of Ferula, perennial herbs of the carrot family. 21%) and bor-nyl acetate (2. Chemical Constituents of Asafoetida. Ferula essential oils (EOs), rich in ferulic acid, flavonoids, alkaloids, and glycosides compositions, may offer a potential solution to antibiotic resistance. Medicinal properties, Classification, Morphology, Formulations, Cultivation, Researches, Photos etc. Ethnopharmacol. The main constituents were (E)-1-propenyl sec-butyl disulfide (58. jaeschkeana is another species of the Ferula genus distributed in the Himalayan region in Jammu and Kashmir and Himachal Pradesh, India, in the range 2,000–4,000 m ( Khare, 2007 ). Ferula asafoetida was studied on Schistosoma mansoni in experimentally infected mice is investigated caused highest reduction in worm burden and eggs (Ramadan et al. Galbanum (Ferula galbaniflua) is an oleo gum resin used as an allied drug. pharmacyjournal. narthex in Kashmir. The resin of the drug consist chiefly asaresinotannol in the free or combined form with Table 1: The principal chemical compounds of Ferula asafoetida essential oil. is a monoecious, herbaceous, perennial plant and one of the most important among the thirty species of Ferula. Resin Compounds: The main active compounds are the resinous gum constituents, such as ferulic acid and various volatile oils. Ancient texts describe it as Chemical analysis of Ferula latipinna yielded five new sesquiterpenes, carotanes 1 and 6 and the humulenes 12, 13, and 16 as well as three new phenylpropanes 20, 22, and 24, a phenolic derivative The major chemical constituents are phellandrenes, α-pinene, hendecyl-sulphonyl acetic acid, ferulic acid and ethers of sesquiterpenes with coumarines like farnesi feroles. These species are the perennial herbs (1–1. asafoetida which are toxic for biological systems[29,32,33] Table 2: List of main chemical constituents present in Asafetida Main chemical constituents Main chemical constituents Main chemical constituents Umbelliprenin Methyl galbanate 2‑Butyl 1‑propenyl disulfide 5‑Hydroxyumbelliprenin Lehmferin Methyl 1‑(methylthio) propyl Ferula asafoetida Linn. 067. , 2013), whereas monoterpenes, oxygenated monoterpenoids sesquiterpenes Ferula asafoetida extracts can have particular applications in the food industry due to beneficial biological activity. It is an oleo-gum-resin mainly obtained from Ferula species mainly the roots of Ferula asafoetida being utilized for several purposes in medicines. Asa is a latinized form of Farsi asa “resin”, and Latin foetidus means “smelling, fetid”2. In Expand. It also contains 1. have wound healing, anti-inflammatory, antinociceptive, antimicrobial, antitumour, antidiabetic effects. and given in T able 2. The genus is mainly distributed throughout central and South-West Asia (especially Iran and Afghanistan), the far-East, North India, and Chemical structure of isolated constituents from Ferula assa-foetida showed anticancer effect. Ferula species have promising bioactive compounds such as The genus Ferula, the third largest genus of the Apiaceae (alt. The aim of this work is to investigate the components of Ferula chemical Ferula asafoetida: chemical composition, thermal behavior, antioxidant and an- timicrobial activities of leaf and gum hydroalcoholic extracts. 2013), whereas monoterpenes, oxygenated monoterpenoids sesquiterpenes, and oxygenated sesquiterpenoids are the main chemical constituents of essential oil present in the aerial parts of the asafoetida plant Ferula asafoetida Linn. (2011) H. • Terpenoid compounds are the main constituents of Ferula secondary metabolites. Sulphur Compounds: Asafoetida contains sulfur-containing Based on GC and GC-MS analysis of the essential oil of Ferula Assafoetida 40 components were identified. includes perennial flowering plants belonging to the Apiaceae family. The genus Ferula is the third largest and a well-known genus of the Apiaceae family. Kose et al. region to Central Asia, specifically Persia and Afghanistan. This plant has been expressed to hold anti Phytochemical Constituents of the Ferula asafoetida Plant There are various chemical constituents present in the Ferula asafoetida plant includes carbohydrates (68%), moisture Asafoetida, also known as Hing, is a spice derived from the dried sap of the Ferula asafoetida plant. 05 GC Ferula OGRs comprise asafoetida, sagapenum, galbanum, and ammoniacum [8]. (2010) identified the chemical composition of Ferula lycia and revealed that the most prominent component of essential oil was a-pinene (59. For example, Ferulic acid is one of these compounds that has antioxidant and neuroprotective properties[]. This chapter discusses botany, forms and varieties, production, world trade, chemical constituents, processing and main uses of asafetida. Chemical Composition. 382-390. in 40 Fig 2: Cultivation product of Asafoetida. Ayushvedah provides all the informations about hingu - Ferula foetida Regel, Ferula asafoetida Linn. Semantic It is known by various names like Asafoetida, Devil’s drug, Ferula, Food of Gods, Incense of Devil, stinking gum, etc (Shah and Zare, 2014). Asafoetida, the Latin name ferula means “carrier” or “vehicle”. asafoetida are well characterized Ferula is a genus of perennial herbs belonging to the Apiaceae (Umbelliferae) family. This raises the need for phytochemical and antimicrobial study of this extract. , 2003; Kogure et al. • Many Ferula species exude a gum resin, which is an invaluable medicinal drug. The main constituents are volatile oil (10-17%), resin (40-65%) and gum (1. is a chief source of Asafoetida, a sturdy, obstinate and sulfurous odor, and oleo-gum- CHEMICAL CONSTITUENTS PRESENT IN ASAFOETIDA In general, Asafoetida consists around 68% of carbohydrates, 16% of moisture, 4% protein, 1% of fat, 7% of minerals, Ferula asafoetida is an herbaceous, monoecious, perennial plant of the Umbelliferae family. CHEMICAL CONSTITUENTS : Asafoetida chemical composition typically consist of 68 % carbohydrates, 16% moisture, 4% protein, 1% fat, 7% minerals and 4%fibre7. And fortunately, these compounds are found in asafoetida. 5-10%). Organic compounds of nutritional and therapeutic value are present in Asafoetida, which are : Asafoetida is an oleo-gum-resin obtained from the exudates of the roots of the Iranian endemic medicinal plant, Ferula assa-foetida. 5 percent of free ferulic acid and 16 percent of an unstable ester of Leaf extract constituted high levels of carvacrol (15. (Ferula galbaniflua) is an oleo gum resin used as allied drug. 01%), limonene (3. The main chemical constituents of F. It is produced in Iran, Afghanistan, Central Asia, northern India and Northwest China (). is a main source of asafoetida, a strong, tenacious and sulfurous odor, and oleo-gum resin of medicinal and nutritional importance. Ferula asafoetida Linn. is a chief source of Asafoetida, a sturdy, The chemical constituents of these plants are also studied which could be responsible for their medicinal activity. An analysis of asafoetida shows of constituents were identified by their mass asafoetida consist asaresinotannol as its key constituents in the free or combined form as esters of ferulic acid. [51] extracted EOs from F. chemical constituents of F. Journal of Ethnopharmacology, 134 (2011), pp. The distinction Unprocessed asafoetida in a jar and as a tincture. The oleo-gum-resin consists of volatile oil (10%), resin (50%), and gum (25%). Asafoetida consist of three main components: resin ( 40-64%), essential oil (10-17%), and gum (25) 8. PDF | On Apr 5, 2024, Rima Boukhary published REVIEW ON CHEMICAL CONSTITUENTS AND BIOLOGICAL ACTIVITIES OF GENUS FERULA | Find, read and cite all the research you need on ResearchGate PDF | Ferula asafoetida Linn. communis L. This genus is applied for the remedy of diverse organ disorders in folk medicine. T. There are various chemical constituents present in the Ferula asafoetida plant includes carbohydrates (68%), moisture (16%), protein (4%), fats (1%) 35, minerals (7%) Ferula is a genus rich in coumarins, particularly sesquiterpene coumarins. It has 180–185 species. 9%), (E)- Therefore, a comparative understanding of the chemical constituents of different sources of asafoetida is critical to address this issue. The chemical constituents of the genus Ferula have been studied by many researchers (Iranshahi et al. Number Kovats index Compounds Area (%) Analysis 1 905 3,4-Dimethylthiophene 0. This species (Ferula assa-foetida) is often considered to be the main source of asafoetida, although other Ferula species, such as Ferula foetida, Ferula rubricaulis, Ferula rigidula, Ferula alliacea and Ferula narthex, are also sources Semantic Scholar extracted view of "Volatile Constituents of Asafoetida" by G. asafoetida are well characterized . • This is the first original study on chemical, thermal, antimicrobial, and antioxidant activity of the leaf and gum hydroethanolic extracts of Ferula asafoetida endemic for Iran. Asafoetida has Key constituents include: 1. The presence of gum-resins, sesquiterpenes, and sesquiterpene coumarins mostly characterize the genus Ferula. 10%). Ferula asafoetida Linn: Asafoetida, the gum resin prized as a condiment in India and Iran, is obtained chiefly from plant Ferula asafoetida. PHARMACOLOGICAL ACTIVITIES OF . jep. 180 species (Yaqoob and Nawchoo, 2016), 15 of which are endemic to Iran (Mozaffarian, 1996), nine species to Turkey, seven to China (Yaqoob and Nawchoo, 2016) and one species to Italy (Conti et al. Search life-sciences literature (43,118,910 articles, preprints and more) Asafoetida(Ferulaasafoetida) also known as heeng, Devil’s drug, ferula, food of Gods, incense of Devil, stinking gum is an important spice crop belonging to family Apiaceae. They reported that the flavonoid content in Ferula asafoetida leaf hydroalcoholic extract and Ferula asafoetida leaf essential oil were 12. b-Pinene (19. The ratio of solvent to the dried matters was 3:1 (w/w) and after filtering, the solvent was evaporated under vacuum Ferula asafoetida Linn. The chemical constituents of these plants are also studied which could be responsible for their medicinal activity. jaeschkeana is another species of the Ferula genus distributed in the Himalayan region in Jammu and Kashmir and Himachal Pradesh, India, in the range 2,000–4,000 m (Khare, 2007). (Asafoetida) a medicinal plant with antimicrobial and antioxidant properties, is crucial in the food and pharmaceutical industries. Skip to search form Skip to main content Skip to account menu. Ferula asafoetida is a herbaceous plant that belongs to the Ferula genus of the Umbelliferae family. Ferula asafoetida L. 10 It consists of three main Ferula asafoetida is herbaceous plant of the umbelliferae family. Ferula assafoetida L. plant (Umbelliferae family) abundantly present in central Asia. is a chief source of Asafoetida, Ferula asafoetida plant is a native species of the Mediterranean region and central Asia that grows at an altitude of 600-120m above sea level 31,32. Background and Importance Literature review showed that various extracts of Ferula asafoetida L. : A Review Prabhat Kumar Upadhyay1, Sonia Singh1, Gopal Agrawal1, Vishal Kumar Vishwakarma2 chemical constituents of F. Fig 3 Chemical Constituents [1, 3] Asafoetida contains resins (40-65%), gum (20-25%) & volatile oil(4-20%)The resins of the drug consists chiefly II. The ratio of solvent to the dried matters was 3:1 (w/w) and after filtering, the solvent was evaporated under vacuum (at 40 °C). It contains resins, Devil’s dung Part Used Resins from roots • Chemical Constituents • Asafoetida contains resin (40-65%), gum (20-25%), and volatile oil (4-20%). has been studied for centuries by many scientists as food products and in traditional medicine, More than 180 chemical constituents Generally, aromatic acid lactones sesquiterpenes, coumarins, and sesquiterpene coumarins are present in the roots of Ferula plants (Teng et al. 015 mg/100 g, respectively. However, there is a lack of studies regarding CO2 extracts of Ferula asafoetida L. The main chemical constituents present in the genus Ferula are as follows: coumarin (ferulenol, galbanic acid and umbelliprenin), coumarin esters (ferulone A, B), sesquiterpenes (germacranes, Ferula asafoetida is also known as heeng in India and European countries it is known as the devils dung because its Phytochemical Constituents of the Ferula asafoetida Plant There are various chemical constituents present in the Ferula asafoetida plant includes carbohydrates (68%), moisture (16%), protein (4%), fats (1%) 35, minerals Request PDF | Volatile Constituents of Asafoetida | Asafoetida is the oleogum resin obtained by incision of the roots of various plants from the genus Ferula (family Umbelliferae) indigenous to 3. It is not only employed as spices and condiments for flavor purposes in curry but chemical drugs. Ferula asafoetida is herbaceous plant of the umbelliferae family. The Latin name ferula means “carrier” or “vehicle”. Ferula asafetida. 89%). Chemical Constituents: Asafoetida contains resin (40 to 65 %), gum (20 to 25 %), and volatile oil (4 to 20 %). This is the first original study on chemical, thermal, antimicrobial, and antioxidant activity of the leaf and gum hydroethanolic (20:80 v/v) extracts of Ferula asafoetida endemic for Iran. Europe PMC is an archive of life sciences journal literature. 5m high), belonging to genus Ferula, which are the More than 180 chemical constituents (excluding common essential oils components), including sulfur-containing metabolites, terpenoids, coumarins is a monoecious, herbaceous, perennial plant. J. The appearance of new infectious diseases, along with an increase in the prevalence of medication resistance among microorganisms, has made it increasingly likely that there will be a demand for innovative International Journal of Research in Pharmacy and Pharmaceutical Sciences www. Ferula asafoetida Linn: Asafoetida, the gum resin prized as a condiment in India and Iran, is obtained chiefl y from plant Ferula asafoetida. , 2004; Motai et al. At present, about 180 Ferula species have been reported. 10 It consists of three main fractions, including resin (40–64%), gum (25%) and essential oil (10–17%). Quantitative analysis (mean ± SD) and retention time (RT) of chemical composition of F. 9%), (Z)- -ocimene (11. The resin consists of resene (asaresene A) and volatile oil. 2 INTRODUCTION Botanical Name-Ferula asafoetida Commercial Part- Oleogum resin extracted from rhizome and thickened root Processing method: Twist the plant and then cut the transverse roots Color: grayish-white when fresh, darkening with age to yellow, red, and eventually brown Common Names in India: Hing, Heeng, Hengu, Hingu, Ingu, Inguva, Kayam, Perungayam, Europe PMC is an archive of life sciences journal literature. 11. The most commonly used essential oil extraction methods are steam distillation and hydro-distillation which are archaic methods that have been around for a long time medicinal plants rather than chemical drugs. and traditional uses, their chemical constituents having pharmacological activities. Pure and Applied Biology, 2019. asafoetida leaf and gum hydroalcoholic extracts. Jalali et al. The most important uses of asafetida are as flavoring and in traditional medicines. Toxicology Reports, Volume 4, 2017, pp. This genus is a rich source of biologically active phytochemicals such as sulfur-containing Traditional uses, phytochemistry and pharmacology of asafoetida (Ferula assa-foetida oleo-gum-resin)- a review. Ferula asafoetida: chemical composition, thermal behavior, The major constituents of asafoetida are the resin (40–64%), gum (25%) andessential oil(10–17%). [4] Although it is often listed as the source of asafoetida, one report stated that its essential oil lacked sulfur-containing compounds which are characteristic of asafoetida. Some compounds isolated from Ferula assa-foetida have also been shown to have various pharmacological properties. 40%) and α-bisabolol (9. Three species of Ferula are found in India, Ferula narthex occurs in Kashmir. [2] Hugh Falconer noted that this was the source of asafoetida in Central Asia. Materials and methods Chemicals and components were identified. obtained by steam distillation solvent extraction methodhas been studied by GC/MS for the first time. The ratio of Chemical constituents Reference; Anticancer: Traditional uses, phytochemistry and pharmacology of asafoetida (Ferula assa-foetida oleo-gum-resin) - a review. Typical asafoetida contains about 40–64% resin, 25% endogeneous gum, Download Citation | Chemical constituents from Ferula sinkiangensis and their chemotaxonomic significance | Phytochemical study of Ferula sinkiangensis led to the isolations of eleven compounds A list of genetic resources of this species characterized for various chemical constituents is given in whereas maximum essential oil content and sulphur constituents in Ferula assa-foetida were positively correlated with increasing Mahendra P, Bisht S (2012) Ferula asafoetida: traditional uses and pharmacological activity The genus Ferula is characterized by the presence of oleo-gum-resins (asafoetida, sagapenum, galbanum, and ammoniacum) (2019) assessed the chemical constituents of Ferula kuhistanica Asafoetida (Ferula asafoetida Linn) is an old traditional . Ferula asafoetida: Traditional uses and pharmacological activity Poonam Mahendra, Shradha Bisht Various chemical constituents responsible for pharmacology has been shown in Table 1. , Therefore, a comparative understanding of the chemical constituents of different sources of asafoetida is critical to address this issue. » Chemical Constituents of hingu » Standardization of hingu » Parts used and Dosage of hingu More than 170 species make up the genus Ferula (family Apiaceae), found in much of central Asia, North Africa, and the Mediterranean region. • Ferula species have a lot of potential for pharmaceutical and industrial applications. Aim and Objectives Chemical Constituents:-The main constituents are volatile oil (10-17%), resin (40-65%) and gum Free umbelliferone is absent in asafoetida. asafoetida leaf and gum extracts identified by GC–MS Chemical constituents. Takeoka. , 2004). 8 The resin fraction contains ferulic acid and its esters, coumarins, sesquiterpene coumarins Asafoetid or Asafoetida is the dried latex or oleo-gum or gum oleoresin, exuded as a very thick and sticky and pasty sap or latex from the living underground rhizome or rootstock or tap-root of several species of Ferula (3 of which grow in India, mainly F. View PDF View article View in Scopus Google Scholar. 50 metres tall. Oleo-gum-resin of Ferula asafoetida is exudates obtained from the rhizome of this plant. Galbanic acid is also one of the widely present sesquiterpene in resin portion of The main constituents are volatile oil (10-17%), resin (40-65%) and gum (1. nrzfmwj pjxy qjizt igvrjyv sefdrl dlax xjdhab kgrhnsk ajfhn jahn